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Generalov I.I., Korotina O.L., Tikhonova S.F., Generalova A.G., Zheleznyak N.V.
Abzyme activity of polyclonal immunoglobulins of IgA class

Abstract.
Isolation of polyclonal IgA from oral fluids of patients with chronic periodontitis and healthy individuals from the control group was conducted. These immunoglobulin samples were tested for the presence of their natural DNAse, proteolytic and redox catalytic activity. Simultaneously with abzyme testing the assessment of DNAse, proteolytic and oxidative activities of initial oral fluids used for primary isolation of IgA was performed. It was determined for the first time that polyclonal IgAs of oral fluids can possess intrinsic DNAse, peroxidase, catalase and proteolytic activity.
Key words: abzymes, DNAse activity, proteolytic activity, catalase activity, peroxidase activity, immunoglobulins, antibodies.

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