Moiseyev D.V.
Antimicrobial activity of medicinal plants, which contain phenolic compounds, depending on the package type and temperature conditions of the storage
Abstract.
Antimicrobial activity of nine kinds of the herbal substances, containing phenolic compounds have been compared. The estimation has been made by the diffusion method to an agar with the use of the following microorganisms strains: Escherichia coli (ATCC 16404), Pseudomonas aeruginosa (ATCC 9027), Bacillus subtilis (ATCC 6633), Staphylococcus aureus (ATCC 6538), and also yeast fungi Candida albicans (ATCC 10231). As reference preparations the solutions of antimicrobial medicinal remedies have been used, such as: gentamycin, cyprofloxacine, cefotaxime, and ceftriaxone in the concentrations from 0,5 to 32 mkg/ml. The activity for four kinds of medicinal plants (flowers of European meadowsweet, leaves of leather bergenia, leaves of cow-berry and leaves of black alder) has been determined. For herbal substances distinct dose dependent effect is observed. On long-term storage in natural conditions the decrease of antimicrobial activity is practically not observed, both for herbal substances in hermetic, and in non-hermetic package. The increase in humidity of the stored herbal substances leads to the decrease of antimicrobial activity.
Key words: antimicrobial activity, European meadowsweet, leather bergenia, cow-berry, black alder.
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