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Myadelets O.D., Myadelets V.O., Sobolevskaya I.S., Kichigina T.N.
White and brown fatty tissues: their interaction with the skeletal muscular tissue

Abstract.
In this literature review new literary as well as the authors’ own data about the functions of white and brown fatty tissues, and their interaction with each other and with the skeletal muscular tissue are presented. Recently new scientific data concerning the sources of brown fatty tissue development have been received. It has been shown that not only infants but also adults have brown fatty tissue. It has also been determined that two types of fatty tissue can transform into each other through the stage of beige fatty tissue. On physical exertion and cold influence the hormone irisin is formed in the skeletal muscles. It contributes to the conversion of white fatty tissue into the brown (or beige) one, decreases the body mass in case of obesity, favourably influences the course of type 2 diabetes mellitus and a number of other diseases associated with aging. It improves mental abilities of a person, because it stimulates the production of neuronal neurotrophic factor BDNF. This factor activates the division of cambial cells in the hippocamp which leads to the improvement of human cognitive abilities.
Key words: white and brown fatty tissues, to convert, hormone, human mental abilities, cambial cells, hippocamp.

References

1. Verbovoy AF, Solomonova ES, Pashentseva AV. Leptin, rezistin i omentin u patsientov s narushennoi tolerantnost'iu k gliukoze i sakharnym diabetom II tipa [Leptin, resistin and omentin in patients with impaired glucose tolerance and type II diabetes]. Izvestiia vysshikh uchebnykh zavedenii. Povolzhskii region. Meditsinskie nauki. 2012;(3):52-9.
2. Kovaleva ON, Ambrosova TN, Ashcheulova TV, Getman EA. Adipokiny: biologicheskie, patofiziologicheskie i metabolicheskie effekty [Adipokina: biological, pathophysiological and metabolic effects]. Vnutrіshnia meditsina. 2009;(3):18-26.
3. Bershtein LM. Endokrinnaia funktsiia zhirovoi tkan, ili kak Vas teper' nazyvat', mister Zh? [Endocrine function of fatty tissue or how now to call you, Mr. Zh?]. Priroda. 2005;(3):9-14.
4. Kosygina AV. Adipotsitokiny v nauchnoi i klinicheskoi praktike [Adipotsitokina in scientific and clinical practice]. Ozhirenie i metabolizm. 2011;(1):32-9.
5. Solntseva AV. Endokrinnye funktsii zhirovoi tkani [Endocrine functions of fatty tissue]. Meditsinskie novosti. 2009;(3):7-11.
6. Chubrieva SYu, Glukhov NV, Zaichik AM. Zhirovaia tkan' kak endo-krinnyi reguliator (obzor literatury) [Fatty tissue as endocrine regulator (review of literature)]. Vestnik Sankt-Peterburgskogo universiteta. Ser. 11, Meditsina. 2008;(1):32-43.
7. Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab. 2004 Jun;89(6):2548-56.
8. Traktuev DO, Parfenova EV, Tkachuk VA, March KL. Stromal'nye kletki zhirovoi tkani – plasticheskii tip kletok, obladaiushchikh vysokim terapevticheskim potentsialom [Stromalny cells of fatty tissue – plastic type of the cells possessing high therapeutic potential]. Tsitologiia. 2006;48(2):83-94.
9. Miadelets OD, Adaskevich VP. Morfofunktsional'naia dermatologiia [Morfofunktsionalny dermatology]. Mosow, RF: Meditsinskaia literatura; 2006. 752 р.
10. Bykov VL. Tsitologiia i obshchaia gistologiia: funktsional'naia mor-fologiia kletok i tkanei cheloveka [Cytology and general histology: functional morphology of cells and tissues of the person]. Saint-Petersburg, RF: Sotis; 1998. 510 р.
11. Sokolov VE, Skurat LN, Stepanova LV, Sumina EB, Shabadash SA. Rukovodstvo po izucheniiu kozhnogo pokrova mlekopitaiushchikh [Study guide of an integument of mammals]. Moscow, RF: Nauka; 1988. 280 р.
12. Klushenkov EP, Miadelets OD. Topografiia i vaskuliarizatsiia buroi zhirovoi tkani beloi besporodnoi krysy [Topography and vascularization of brown fatty tissue of a white not purebred rat]. V: X s"ezd Belorusskogo obshchestva fiziologov: tez. dok. Minsk, RB; 2001. р. 72-73.
13. Miadelets OD, Klushenkov EP. Morfologiia buroi zhirovoi tkani u laboratornykh krys [Morphology of brown fatty tissue at laboratory rats]. V: Funktsional'naia neiromorfologiia. Fundamental'nye i prikladnye issledovaniia. Minsk, RB; 2001. р. 334-337.
14. Medvedev LN, Elsukova EI. Buraia zhirovaia tkan': molekuliarnye osnovy reguliruemogo termogeneza [Brown adipose tissue: the molecular basis of regulated thermogenesis]. Krasnoyarsk, RF: Amal'gama; 2002. 528 р.
15. Medvedev LN, Elsukova EI. Buraia zhirovaia tkan' cheloveka [Brown fatty tissue of the person]. Uspekhi fiziologicheskikh nauk. 2002;33(2):17-29.
16. Medvedev LN, Elsukova EI. Vliianie estestvennogo perekorma molodniaka na buruiu zhirovuiu tkan' [Influence of a natural reforage of young growth on brown fatty tissue]. Ontogenez. 1999;30(1):61-3.
17. Murashkin TV. Liuminestsentnaia morfologiia mezhlopatochnoi buroi zhirovoi tkani [Luminescent morphology of interscapular brown fatty tissue]. V: Eksperimental'naia i prikladnaia morfologiia: mezhvuz. sb. nauch. tr. Cheboksary, RF; 1988. р. 80-84.
18. Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S,Højlund K, Gygi SP, Spiegelman BM. PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012 Jan;481(7382):463-8.
19. Ferrer-Martínez A, Ruiz-Lozano P, Chien KR. Mouse PeP: a novel peroxisomal protein linked to myoblast differentiation and development. Dev Dyn. 2002 Jun;224(2):154-67.
20. Afanasiev YuI, Kolodeznikova ED. Buraia zhirovaia tkan' [Brown adipose tissue]. Irkutsk, RF: IGU; 1995. 184 р.
21. Erickson HP. Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor? Adipocyte. 2013 Oc;2(4):289-93.
22. Zhang Y, Li R, Meng Y, Li S, Donelan W, Zhao Y, Qi L, Zhang M, Wang X, Cui T, Yang LJ, Tang D. Irisin Stimulates Browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling. Diabetes. 2014 Feb;63(2):514-25.
23. Wrann CD, White JP, Salogiannnis J, Laznik-Bogoslavski D, Wu J, Ma D, Lin JD, Greenberg ME, Spiegelman BM. Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway. Cell Metabolism. 2013 Nov;18(5):649-59.
24. Teufel A, Malik N, Mukhopadhyay M, Westphal H. Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes. Gene. 2002 Sep;297(1-2):79-83.

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