Menu

A+ A A-

Download article

DOI: https://doi.org/10.22263/2312-4156.2018.3.76

Katina M.A., Lesnichaya O.V.
The case of cutaneous pseudolymphoma (cutaneous lymphoid hyperplasia) against the background of untreated scabies
Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus

Vestnik VGMU. 2018;17(3):76-83.

Abstract.
The article presents the definition and classification of cutaneous pseudolymphoma, the attention is paid to the principles of differential diagnosis of cutaneous lymphoma using immunohistochemical, clinical-histological, molecular-genetic methods of diagnosing. In some cases, additional instrumental and laboratory studies are needed to assess the general status of the patient. There is also the review of possible exogenous causes, clinical manifestations and methods of cutaneous lymphoid hyperplasia treatment. A clinical case of cutaneous lymphoid hyperplasia with typical histological features against the background of untreated scabies is described. Clinical manifestations of the disease were the grouped symmetrical nodular lesions with a smooth surface without scaling in axillar regions, accompanied by moderate itching. A primary diagnosis made was «prurigo». On a detailed history taking and physical examination, small papules in the places of typical for scabies localization accompanied by the universal itching of the skin were observed. Typical histological findings confirming the cutaneous lymphoid hyperplasia caused by anthropoid infection were the following: intact epidermis, Grens zone, polymorphic diffuse lymphocytic infiltrate with plasmatic cells and numerous eosinophils.
Key words: pseudolymphoma, cutaneous lymphoid hyperplasia, scabies, cutaneous lymphoma.

References

1. Olisova OYu, Teplyuk NP, Garanyan LG, Pyatilova PM. Benign lymphopenia skin that developed on the location of the tattoo. Ros Zhurn Kozh Vener Boleznei. 2015;18(2):23-6. (In Russ.)
2. Potekaev NS, Olisova OYu, Galil-Ogly GA. Diagnosis of true pseudolymphoma of the skin. Mezhdunar Med Zhurn. 2003;(2):117-20. (In Russ.)
3. Teplyuk NP, Belousova TA, Grabovskaya OV, Nikuradze VO. Benign lymphoplasma of the skin: diagnosis and treatment. CONSILIUM MEDICUM. Dermatologiia. 2017;(2):40-3. (In Russ.)
4. Bergman R. Pseudolymphoma and cutaneous lymphoma: facts and controversies. Clin Dermatol. 2010 Sep-Oct;28(5):568-74. doi: http://dx.doi.org/10.1016/j.clindermatol.2010.04.005
5. Bergman R, Khamaysi K, Khamaysi Z, Ben Arie Y. A study of histologic and immunophenotypical staining patterns in cutaneous lymphoid hyperplasia. J Am Acad Dermatol. 2011 Jul;65(1):112-24. doi: http://dx.doi.org/10.1016/j.jaad.2010.07.003
6. Bergman R, Khamaysi Z, Sahar D, Ben-Arieh Y. Cutaneous lymphoid hyperplasia presenting as a solitary facial nodule: clinical, histopathological, immunophenotypical, and molecular studies. Arch Dermatol. 2006 Dec;142(12):1561-6. doi: http://dx.doi.org/10.1001/archderm.142.12.1561
7. Sarantopoulos GP, Palla B, Said J, Kinney MC, Swerdlow SM, Willemze R, et al. Mimics of Cutaneous Lymphoma Report of the 2011 Society for Hematopathology/European Association for Haematopathology workshop. Am J Clin Pathol. 2013 Apr;139(4):536-51. doi: http://dx.doi.org/10.1309/AJCPX4BXTP2QBRKO
8. Kutlubay Z, Pehlivan O, Engin B. Cutaneous Pseudolymphomas. J Turk Acad Dermatol. 2012;6(3):1263r1.
9. Kaveh GH, Rana R, Zeinab AS, Behnam R. Miliarial type pseudolymphoma mimicking as granulomatous rosaceaю Our Dermatol Online [Internet]. 2017 [cited 2018 Apr 16];8(3). Available from: http://www.odermatol.com/odermatology/20173/22.Miliarial-KavehGN.pdf.
10. Lackey JN, Xia Y, Cho S, Sperling LC. Cutaneous lymphoid hyperplasia: a case report and brief review of the literature. Cutis. 2007 Jun;79(6):445-8.
11. Moulonguet I, Ghnassia M, Molina T, Fraitag S. Miliarial-type perifollicular B-cell pseudolymphoma (lymphocytoma cutis): a misleading eruption in two women. J Cutan Pathol. 2012 Nov;39(11):1016-21. doi: http://dx.doi.org/10.1111/cup.12010

Information about authors:
Katina M.A. – Candidate of Medical Sciences, associate professor of the Chair of Dermatovenerology, Vitebsk State Order of Peoples’ Friendship Medical University;
Lesnichaya O.V. – Candidate of Medical Sciences, associate professor of the Chair of Pathologic Anatomy with the course of Forensic Medicine, Vitebsk State Order of Peoples’ Friendship Medical University.

Correspondence address: Republic of Belarus, 210023, Vitebsk, 27 Frunze ave., Vitebsk State Order of Peoples’ Friendship Medical University, Chair of Dermatovenerology. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Mariya A. Katina.

Поиск по сайту