DOI: https://doi.org/10.22263/2312-4156.2019.2.74
Bondarenko V.M.
Determination of the cut-off ultrasound values of the perirenal visceral adipose tissue amount in patients with metabolic syndrome
Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
Vestnik VGMU. 2019;18(2):74-80.
Abstract.
Objectives. To determine the cut-off ultrasound values of perirenal visceral adipose tissue (VAT) amount in patients with metabolic syndrome (MS) and in healthy subjects, using various ultrasound techniques.
Materials and methods. 162 patients, including 103 men and 59 women, were enrolled in this cross-sectional study. The average age of the patients was Me (25th and 75th quartile) 43.00 (36.00; 48.00). Out of all persons, 96 patients had MS and 66 were healthy subjects.
Ultrasound measurements of the thickness of visceral adipose tissue in the posterior perirenal space (PPVAT) and the thickness of the anterior perirenal visceral adipose tissue (APVAT) on the right side, as well as the thickness of para- and perirenal fat (PAPEVAT) and the area of the inferior part of the perirenal visceral adipose tissue (AIPVAT) from the both sides were performed in all patients. ROC analysis was used to determine the cut-off values of the enumerated parameters between healthy subjects and patients with MS.
Results. The amount of perirenal VAT, measured by all four methods is significantly higher in patients with MS compared with the same indicators in the control group (p<0.001). For all this the differences between all values of perinephral VAT in men and women with MS were statistically insignificant. The cut-off value of the PPVAT amount made up 8.2 mm, that of APVAT –2.2 mm, PAPEVAT 28.9 mm and AIPVAT – 21.1 сm2.
The area under the ROC curve (AUC) for ultrasound parameters characterizing the amount of PPVAT, APVAT and PAPEVAT testifies to good and very good quality of the model, and amounted to 0.845, 0.827 and 0.783, respectively. AUC for AIPVAT represents the excellent quality of the model (0.972).
Conclusions. The obtained results demonstrate that the ultrasound parameters of the amount of perirenal visceral adipose tissue in patients with MS are significantly higher than those in healthy individuals. The determined cut-off values of these parameters can be proposed for the use in order to identify patients with the risk of developing MS, the measurement of AIPVAT being more significant.
Key words: perirenal visceral adipose tissue, ultrasound investigation, metabolic syndrome.
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Information about authors:
Bondarenko V.M. – postgraduate of the Chair of Internal Medicine No.2 of the Faculty for Advanced Training & Retraining, senior teacher of the Chair of Hospital Surgery with the courses of Urology & Pediatric Surgery, Vitebsk State Order of Peoples’ Friendship Medical University.
Correspondence address: Republic of Belarus, 210009, Vitebsk, 27 Frunze ave., Vitebsk State Order of Peoples’ Friendship Medical University, Chair of Internal Medicine No.2 of the Faculty for Advanced Training & Retraining. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Vladimir M. Bondarenko.
