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DOI: https://doi.org/10.22263/2312-4156.2021.1.111

Prudnikov A.R.1, Yanchanka U.V.1, Sidarenka V.F.2, Nikolskaya V.V.2
Clinical case of secondary immunodeficiency against the background of acquired hypercholesterolemia
1Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
2Vitebsk Regional Clinical Hospital, Vitebsk, Republic of Belarus

Vestnik VGMU. 2021;20(1):111-119.

Abstract.
A clinical case of secondary immunodeficiency of mild severity against the background of unbalanced nutrition (food cholesterol deficiency) with a clinical pattern of recurrent upper respiratory tract infections and compensatory hypercholesterolemia of mild degree is presented. The patient had a deficiency of T-helper cells with the increase of total cholesterol and low-density lipoproteins. The patient was prescribed a meal enriched with cholesterol. After 5 months, almost complete normalization of the lipid profile and parameters of T-cell immunity was observed. The intake of food enriched with cholesterol contributed to the normalization of lipoprotein metabolism and T-cell immunity indicators and led to an adequate immune response to the introduced infection.
Key words: secondary immunodeficiency, hypercholesterolemia, T-cell immunity, viral infection.

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Information about authors:
Prudnikov A.R. – Master of Medical Sciences, senior lecturer of the Chair of Hospital Therapy & Endocrinology with the course of the Faculty for Advanced Training & Retraining, Vitebsk State Order of Peoples’ Friendship Medical University.
ORCID: https://orcid.org/0000-0001-9458-0867;
Yanchanka U.V. – Candidate of Medical Sciences, associate professor of the Chair of Clinical Immunology and Allergology with the course of the Faculty for Advanced Training & Retraining, Vitebsk State Order of Peoples’ Friendship Medical University,
ORCID: https://orcid.org/0000-0002-9355-8534;
Sidarenka V.F. – laboratory diagnosis specialist, Vitebsk Regional Clinical Hospital;
Nikolskaya V.V. – laboratory diagnosis specialist, Vitebsk Regional Clinical Hospital.

Correspondence address: Republic of Belarus, 210009, Vitebsk, 27 Frunze ave., Vitebsk State Order of Peoples’ Friendship Medical University, Chair of Hospital Therapy & Endocrinology with the course of the Faculty for Advanced Training & Retraining. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Alexander R. Prudnikov.

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