Denisenko A.G., Yablonsky M.F.
The importance of the immunological criteria of the remoteness of death
Abstract. To establish the remoteness of death (RD) methods of assessment of the dynamic changes of neutrophil metabolic activity (the spontaneous and induced NBT-test), T- and B-lymphocytes expressing CD3, CD4, CD8, CD22, CD25 molecules of erythrocytic diagnosticum sets were worked out. The changes of NBT-test and the amount of T- and B-lymphocytes expressing molecules-markers CD3, CD4, CD8, CD25, CD22 were found out. In persons who died of ischemic heart disease (IHD), poisoning with ethyl alcohol and other causes of death statistically significant decrease in neutrophil functional activity indices was determined by the end of 2 days from the moment of death. It was established that in the postmortem period in persons, who died of mechanical traumas and asphyxias as a result of hanging the quantity of T- and B-lymphocytes expressing CD3, CD4, CD8, CD22, CD25 molecules changed with the suppression of their activity up to 65-78 hours after death.
Key words: remoteness of death, NBT-test, T- and B-lymphocytes, expression of CD3, CD4, CD8, CD22, CD25 molecules.