DOI: https://doi.org/10.22263/2312-4156.2018.2.20
Gorodetskaya I.V., Masyuk N.Yu.
The effect of iodine-containing thyroid hormones on the tissues of the maxillofacial area
Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
Vestnik VGMU. 2018;17(2):20-29.
Abstract.
The change in the level of iodine-containing thyroid hormones results in a number of negative consequences in the body, including the damage to the maxillofacial area tissues. The main dental manifestations of the thyroid dysfunction, i.e. disruption in the formation and eruption of temporary and permanent teeth, their carious lesion, inflammatory and degenerative processes in the periodontium and gums, destruction of the alveolar bones of the jaws have been studied and summarized. The review deals with the analysis of those factors that reduce the resistance of the oral cavity tissues, as well as the determination of their alteration mechanisms (stimulation of lipid peroxidation and proteolysis, depression of the activity of antioxidant systems, decrease in the rate of salivation, disturbance of the ionic composition of the saliva, the ratio between the activity of acidic and alkaline phosphatases in it, suppression of the local immunity, damaged microcirculation in the dental pulp). Special attention is paid to establishing the possibility of increasing the resistance of the enamel, dentin and their surrounding tissues to stress by means of the purposeful correction of the thyroid status.
Key words: hypothyroidism, hyperthyroidism, caries, saliva.
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Information about authors:
Gorodetskaya I.V. – Doctor of Medical Sciences, professor of the Chair of Normal Physiology, dean of the Medical Faculty, Vitebsk State Order of Peoples’ Friendship Medical University;
Masyuk N.Yu. – postgraduate of the Chair of Normal Physiology, Vitebsk State Order of Peoples’ Friendship Medical University.
Correspondence address: Republic of Belarus, 210023, Vitebsk, 27 Frunze ave., Vitebsk State Order of Peoples’ Friendship Medical University, Chair of Normal Physiology. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Natalya Yu. Masyuk.
