DOI: https://doi.org/10.22263/2312-4156.2018.5.17
Sobolevskaya I.S., Myadelets O.D., Semenov V.M., Zykova O.S., Sobolevskiу S.L., Pashinskaya E.S.
Structural and functional features of some genes involved in lipid metabolism and transport
Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
Vestnik VGMU. 2018;17(5):17-27.
Abstract.
The study of the genetic aspects of the regulation of lipid metabolism at the present time acquires special significance. To develop a complete differentiated approach in assessing the initiation and progression of metabolic processes disorders, it is necessary to use molecular-genetic markers that allow to make a more accurate diagnosis and also to control the efficacy of the provided treatment. In this respect, the study of genes involved in the metabolism of lipids, combined with biochemical and structural-functional data, will enable the determination of risk of fat metabolism disturbances development in the skin, and will form the basis of predictive medicine and help to implement differential preventive approaches, carry out targeted diagnosing, prevention and treatment of pathologies, taking into account individual peculiarities.The purpose of this article was to generalize and systematize the materials of studying the genetic aspects of lipid metabolism regulation at the present stage for their further use in the original study.
Key words: gene, expression, protein, cell, lipid metabolism, human being.
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Information about authors:
Sobolevskaya I.S. – Candidate of Biological Sciences, associate professor, doctoral candidate of the Chair of Histology, Cytology & Embryology, Vitebsk State Order of Peoples’ Friendship Medical University;
Myadelets O.D. – Doctor of Medical Sciences, professor, head of the Chair of Histology, Cytology & Embryology, Vitebsk State Order of Peoples’ Friendship Medical University;
Semenov V.M. – Doctor of Medical Sciences, professor, head of the Chair of Infectious Diseases, Vitebsk State Order of Peoples’ Friendship Medical University;
Zykova O.S. – Candidate of Medical Sciences, associate professor of the Chair of Dermatovenerology, Vitebsk State Order of Peoples’ Friendship Medical University;
Sobolevskiу S.L. – lecturer of the Chair of Hospital Surgery with the course of Urology and Pediatric Surgery, Vitebsk State Order of Peoples’ Friendship Medical University;
Pashinskaya E.S. – Candidate of Biological Sciences, associate professor, doctoral candidate of the Chair of Infectious Diseases, Vitebsk State Order of Peoples’ Friendship Medical University.
Correspondence address: Republic of Belarus, 210009, Vitebsk, 27 Frunze ave., Vitebsk State Order of Peoples’ Friendship Medical University, Chair of Histology, Cytology & Embryology. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Irina S. Sobolevskaya.
