DOI: https://doi.org/10.22263/2312-4156.2018.5.52
Egorova E.S.
The development of chiasmatic syndrome in pituitary adenoma with suprasellar spreading. Observation peculiarities
Institute of Neurosurgery Named after the Academician A.P. Romodanov of the Ukrainian NAMS, Kiev, Ukraine
Vestnik VGMU. 2018;17(5):52-57.
Abstract.
Objectives. To study the features of chiasmatic syndrome in patients with suprasellar pituitary adenomas (PA) in the observation dynamics.
Material and methods. We observed 96 patients with suprasellar PA. Clinico-neurological, ophthalmological and neurovisualization methods were used for examination.
Results. Сhiasmatic syndrome was observed in 50 (52%) patients with suprasellar PA. It was found that up to 6 months duration of the disease predominated in the main group consisting of 45-59 aged patients with mainly hormonal-inactive PA. In the clinical course of the disease symmetrical chiasmatic syndrome prevailed (58%). In the early postoperative period, the recovery and improvement of vision function occurred: complete recovery – in 10 (20%) patients, improvement in one or both eyes – in 38 (76%) patients, there was no dynamics – in 2 (2%) patients, impairment was not observed.
Conclusions. Suprasellar PA was characterized by the development of chiasmatic syndrome in 52% of patients in whose clinical course bitemporal hemianopia, symmetrical moderate decrement in visual acuity and primary compression optic atrophy dominated. As a result of neurosurgical treatment of PA, the average visual acuity index improved from 0,55±0,04 to 0,75±0,03 (p<0,05) and the index of the mean overall light sensitivity loss improved from 12,13±0,56 dB to 6,49±0,56 dB (p<0,05).
Key words: pituitary adenoma, chiasmatic syndrome, optic atrophy.
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Information about authors:
Egorova E.S. – Candidate of Medical Sciences, neuroophthalmologist, Institute of Neurosurgery Named after the Academician A.P. Romodanov of the Ukrainian NAMS.
Correspondence address: Ukraine, 04050, Kiev, 32 Platona Mayborody (Manuilskogo) str., Institute of Neurosurgery Named after the Academician A.P. Romodanov of the Ukrainian NAMS. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Ekaterina S. Egorova.
