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Hreben M.I., Yaromenka Y.E., Karnialiuk V.A., Kаtovich Н.N.
Morpho-functional state of the mucous membrane of the nasal cavity after surgical treatment
Republican Scientific and Practical Centre of Otorhinolaryngology, Minsk, Republic of Belarus

Vestnik VGMU. 2018;17(5):66-73.

In the presented research, the morpho-functional state of the mucous membrane of the nasal cavity after surgical treatment was studied. The respiratory function of the nasal cavity and rhinoscopic picture after surgical treatment are restored much faster than the functional state of the nasal mucosa: the nasal cycle amplitude and mucociliary transport. The endoscopic picture and the respiratory function of the nasal cavity significantly improved in 77,5% of the patients in 1 month after surgery, with the complete recovery in all the patients in 3 months after surgery.
In the early postoperative period (after 7 days) the pronounced increase in the saccharin time (mean value 32,5±1,7 minutes) was revealed, which was caused by the operative injury and the inflammatory and reparative processes caused by it. In 1 month after the operation, the average value made up 22,2±1,2 minutes, the recovery continued during 3 months after the operation and this value reached 15,9±3,4 minutes. Thus, the function of the mucociliary transport was restored in 87,5% of the patients only in 3 months after the surgical intervention.
The absence of the nasal cycle in the early postoperative period (up to 7 days) and in 1 month after the operation was revealed. In 3 months after the surgical treatment the amplitude of the nasal cycle was restored in the majority of patients (91,7%) (p<0,05). The species of the nasal cycle and its duration after the operation did not change, the non classical two-sided fluctuating nasal cycle predominated, which confirms the leading significance of the vegetative nervous system in the generation of the cyclic changes.
Key words: morpho-functional state, mucous membrane of the nasal cavity, nasal cycle, postoperative period.


1. Derzhavina LL, Kozlov VS, Shilenkova VV. Acoustic rhinometry and anterior active rhinomanometry in the study of the nasal cycle. Ros Rinologiia. 2002;(1):4-10. (In Russ.)
2. Kozlov BC, Kramnoy AI, Derzhavina LL, Averin AA, Lukashevich YuA. Issledovanie mertsatel'nogo epiteliia polosti nosa in vitro. Ros Rinologiia. 2005;(4):22-5. (In Russ.)
3. Krasnozhen VN. Clinical study of mucociliary transport activity in the mucous membranes of the paranasal sinuses. Ros Rinologiia. 2001;(2):107. (In Russ.)
4. Lopatin AS. Rhinitis: ruk dlia vrachei. Moscow, RF: GEOTAR-Media; 2010. 417 р. (In Russ.)
5. Piskunov GZ, Piskunov SZ, Kozlov VS, Lopatin AS. Diseases of the nose and paranasal sinuses. Endomicro surgery. Moscow, RF: Sovershenno sekretno; 2003. 208 р. (In Russ.)
6. Piskunov GZ. Clinical rhinology: ruk dlia vrachei. 2-e izd ispr i dop. Moscow, RF: MIA; 2006. 560 р. (In Russ.)
7. Pukhlik SM, Aleksandrov AD. Interventions on the lower nasal conchae in chronic rhinitis. Rinologіia. 2008;(3):61-8. (In Russ.)
8. Clement PA. Committee report on standardization of rhinomanometry. Rhinology. 1984 Sep;22(3):151-5.
9. Rikhel'man G, Lopatin AG. Mucociliary transport: experimental and clinical evaluation. Ros Rinologiia. 1994;(4):33-47. (In Russ.)
10. Frolov AV. Control of mechanisms of adaptation of cardiac activity in clinic and sports. Minsk, RF: Poliprint; 2011. 216 р. (In Russ.)

Information about authors:
Hreben M.I. – Candidate of Medical Sciences, director of the Republican Scientific and Practical Centre of Otorhinolaryngology;
Yaromenka Y.E. – Doctor of Medical Sciences, associate professor, head of the scientific-research department, Republican Scientific and Practical Centre of Otorhinolaryngology;
Karnialiuk V.A. – postgraduate, Republican Scientific and Practical Centre of Otorhinolaryngology;
Katovich H.N. – research officer, Republican Scientific and Practical Centre of Otorhinolaryngology.

Correspondence address: Republic of Belarus, 220113, Minsk, 45 L. Bedy str., 119. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Volha A. Karnialiuk.

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