DOI: https://doi.org/10.22263/2312-4156.2018.6.85
Klymenko V.A., Karpushenko J.V., Kozhyna O.S.
The results of the phase IV study of ISAAC (International study of asthma and allergy in childhood) in Kharkov Region
Kharkov National Medical University, Kharkov, Ukraine
Vestnik VGMU. 2018;17(6):85-91.
Abstract.
Objectives. The improve bronchial asthma diagnosing in pediatric population of Ukraine by means of ISAAC (International Study of Asthma and Allergy in Childhood) phase IV implementation.
Material and methods. For the first time in Ukraine in 2015-2018 in Kharkov Region phase IV of the International program ISAAC was realized within the frames of the international co-operation with Global Asthma Network Organization. In accordance with ISAAC’s standardized techniques 5926 schoolchildren in Kharkov and 6330 schoolchildren in the districts of Kharkov Region (12256 children in total) were questionnaired in order to estimate the prevalence and severity of bronchial asthma respiratory symptoms. The results of phase IV were compared with those received during phase I (Ognev V.A., 1998) and phase III (Ognev V.A., 2002) of ISAAC to reveal the dynamics of the prevalence and severity of bronchial asthma in pediatric population of Kharkov Region. 70 patients with bronchial asthma were examined according to the national guideline – unified clinical protocol of primary, secondary (specialized), tertiary (highly specialized) medical care «Bronchial asthma in children», approved by the order of the Ukrainian Ministry of Health dated 08.10.2013 No. 868. Statistical processing of the data was done using SQlite / MySql database by parameter statistics method.
Results. 675 schoolchildren who were given questionnaires refused to take part in the study which amounted to 5,5% of the respondents. The answers of 6659 children aged from 6 to 7 years (3238 of them live in the city and 3421 live in the region’s districts) and 4922 teen-agers aged from 13 to 14 years were analyzed. Actual prevalence of wheezing among 6-14 year-old children in Kharkov Region is 4,5% without any significant difference between the urban and rural dwellers. Severe forms of BA are rare in the modern period (up to 0,7%). Prevalence and severity rates of bronchial asthma in Ukraine are average for the Northern and Eastern Europe region. During the past 20 years declining tendencies in both the prevalence (2 times) and severity (3 times) of bronchial asthma were observed. Both in the city (1,6%) and in the countryside (0,5%) the level of asthma diagnosing is rather low. The main clinical features of bronchial asthma in 70 children, examined and treated in accordance with the modern international standards were described.
Conclusions. The implementation of the International program ISAAC helps to improve the early diagnosing of asthma.
Key words: children, bronchial asthma, prevalence, Kharkov Region, ISAAC.
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Information about authors:
Klymenko V.A. – Doctor of Medical Sciences, professor, head of the Chair of Pediatrics Propedeutics No. 2, Kharkov National Medical University,
ORCID: https://orcid.org/0000-0002-6762-9650
Karpushenko J.V. – Candidate of Medical Sciences, associate professor of the Chair of Pediatrics Propedeutics No. 2, Kharkov National Medical University;
KozhynaO.S. – postgraduate of the Chair of Pediatrics Propedeutics No. 2, Kharkov National Medical University.
Correspondence address: Ukraine, 61022, Kharkov, 4 Nauky ave., Kharkov National Medical University, Chair of Pediatrics Propedeutics No. 2. Е-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Olga S. Kozhyna.
