The development of arterial hypertension and the assessment of risk factors influence in the organized population (data of the ten-year prospective study)
1Gomel State Medical University, Gomel, Republic of Belarus
2Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
Vestnik VGMU. 2019;18(2):53-59.
Objectives. To identify risk factors for the development of arterial hypertension (AH) in the organized population.
Material and methods. We conducted clinical-epidemiological survey of LLC «Naftan-Polimir» in 2004-2014 that included 1,431 subjects, out of which 460 persons worked without harmful working factors and 971 worked with unfavorable working factors.
Results. A significant positive relationship was found between the incidence of new hypertension cases and the work in harmful working conditions (df=1; χ2 of the Wald test=5.7; p<0.05), the strongest connection was found to be with psychophysiological factors, characterizing labor intensity (df=1; χ2 of the Wald test =7.3; p<0.01). The significant factors affecting new cases of hypertension after correction for age, sex and factor of the professional activity were identified: systolic (p<0.001) and diastolic blood pressure (p<0.001), heredity (p<0.01), absence of higher education (p<0.001), smoking in the past and present (p<0.001), alcohol abuse (p<0.001), low physical activity (p<0.001), the amount of ECG peaks SV1+RV5–V6 (p<0.001), body mass index (p<0.001), level of salt taste threshold (p<0.001), level of triglycerides (p<0.01) and GFR (p<0.01) according to multifactorial regression analysis.
Conclusions. New cases of hypertension were reliably associated both with the most common risk factors and with the factor of professional activity. Psychophysiological factors of labor intensity had the strongest influence on the latter.
Key words: arterial hypertension, risk factors, preventive examination.
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Information about authors:
Ukla A.A. – lecturer of the Chair of Internal Diseases No. 1 with the course of Endocrinology, Gomel State Medical University.