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DOI: https://doi.org/10.22263/2312-4156.2022.2.70

Tserakhava T.N., Pohodenko-Chudakova I.O., Nijiati N., Yudina O.A.
Comparison of the results of morphological examination at different periods of laser therapy integration into complex treatment for experimental periostitis
Belarusian State Medical University, Minsk, Republic of Belarus

Vestnik VGMU. 2022;21(2):70-78.

Abstract.
Objectives. To carry out a comparative assessment of the results of morphometric study of infectious and inflammatory focus and the density of vessels of the microcirculatory bed at different periods of laser radiation application in the postoperative treatment for experimental periostitis of the jaws.
Material and methods. The experiment was performed on 56 rabbits. 54 of them had simulated acute purulent periostitis (APP) of the lower jaw. All the animals were divided into the following series. Series 1 – 12 rabbits which, after the creation of the APP model, were treated with laser therapy on the 1st, the 3rd and the 5th days after surgery. Series 2 – 16 rabbits which underwent laser therapy treatment on the 3rd, the 5th and the 7th days after surgery. Series 3 (control) – 26 rabbits which were not treated after the creation of the APP model. Series 4 – 2 animals whose jaw fragments were taken as a standard.
Results. In all series 1 micropreparations, after completing the experiment the changes can be characterized as minimally residual inflammatory ones. Complex treatment of periostitis, including laser treatment, applied from the first day of the postoperative period, is effective for relieving infectious inflammation and creating optimal conditions for tissue regeneration.
Conclusions. Despite the similarity of the schemes of complex postoperative treatment for experimental periostitis using the effect of laser on the focus of inflammation in series 1 and 2, it has been found that its positive influence is due to a greater degree of complementarity when used as early as possible after surgery.
Key words: odontogenic infection, acute purulent periostitis, experiment, complex treatment, laser therapy, morphological study.

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Information about authors:
Tserakhava T.N. – Doctor of Medical Sciences, professor of the Chair of Pediatric Dentistry, Belarusian State Medical University,
ORCID: http://orcid.org/0000-0003-2647-5082
Pohodenko-Chudakova I.O. – Doctor of Medical Sciences, professor, head of the Chair of Oral Surgery, Belarusian State Medical University,
ORCID: http://orcid.org/0000-0002-0353-0125
Nijiati N. – postgraduate of the Chair of Pediatric Dentistry, Belarusian State Medical University,
ORCID: http://orcid.org/0000-0003-4895-2281
Yudina O.A. – Candidate of Medical Sciences, associate professor of the Chair of Pathological Anatomy, Belarusian State Medical University,
ORCID: http://orcid.org/0000-0001-7623-0601

Correspondence address: Republic of Belarus, 220116, Minsk, 83 Dzerzhinskogo ave., Belarusian State Medical University, Chair of Oral Surgery. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Irina O. Pohodenko-Chudakova.

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