DOI: https://doi.org/10.22263/2312-4156.2022.4.79
D.V. Turluk1, V.A. Yanushko2, V.Y. Khryshchanovich1, S.A. Alekseev1, O.F. Kardash1, T.V. Svinkovskaya3, N.A. Pinchuk3, M.A. Kruglikova3, E.G. Kordzakhia4
Neuropsychological testing as a screening method for diagnosing cognitive-affective cerebellar syndrome in patients with vertebrobasilar insufficiency
1Belarusian State Medical University, Minsk, Republic of Belarus
2Republican Scientific and Practical Centre «Cardiology», Minsk, Republic of Belarus
3Republican Scientific and Practical Centre of Neurology and Neurosurgery, Minsk, Republic of Belarus
4The 5th City Clinical Hospital, Minsk, Republic of Belarus
Vestnik VGMU. 2022;21(4):79-88.
Abstract.
The study of cognitive deficits in patients with cerebellar pathology led in 1998 to the discovery by J. Schmahmann and J. Sherman of the cognitive-affective cerebellar syndrome (CACS). However, the question of the presence of CACS in patients with circulatory disorders in the posterior cranial fossa with clinical manifestations of cerebellar dysfunction remains unclear.
Objectives. To assess the presence and severity of CACS in patients with chronic vertebrobasilar insufficiency (VBI) caused by extravasal compression of the vertebral arteries in the bone canal.
Material and methods. The study included 114 patients with systemic and non-systemic dizziness. Patients were divided into groups. Тhe first group consisted of 61 patients with severe cognitive deficits, the second group was composed of 53 patients with moderate cognitive deficits, the third group consisted of 20 healthy people. The average age was 48.1+0.8 years (43% – males). The tests were conducted according to the Tinetti scales and the original VBI scale. To assess CACS, testing was carried out using the Folstein, Luria, Bourdon tests.
Results. Patients with VBI experienced attention deficits, emotional control deficits, had autism spectrum symptoms, psychotic spectrum symptoms, and social skills deficits. The degree of cognitive deficit manifestation in the groups of patients was found to depend on the severity of VBI symptoms. The direct correlation between the degree of cognitive impairments and the degree of clinical manifestations of VBI made up 0.68 (r).
Conclusions. Circulatory insufficiency in the posterior cranial fossa is accompanied by a significant decrease in cognitive function against the background of ataxia and other symptoms specific for cerebellar damage, verified by the Tinetti scales and the original VBI scale.
Keywords: Schmahmann’s syndrome, cerebellum, vertebrobasilar insufficiency, vertebral arteries, carotid arteries.
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Information about authors:
D.V. Turluk – doctoral student of the Chair of General Surgery, Belarusian State Medical University,
E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Dmitry V. Turluk;
V.A. Yanushko – Doctor of Medical Sciences, professor, chief researcher of the Laboratory of Vascular Surgery, RSPC “Cardiology”;
V.Y. Khryshchanovich – Doctor of Medical Sciences, professor of the Chair of General Surgery, Belarusian State Medical University;
S.A. Alekseev – Doctor of Medical Sciences, professor of the Chair of General Surgery, Belarusian State Medical University;
O.F. Kardash – Candidate of Medical Sciences, associate professor of the Chair of Clinical Pharmacology, Belarusian State Medical University;
T.V. Svinkovskaya – doctor of functional diagnostics, Republican Scientific and Practical Centre of Neurology and Neurosurgery;
N.A. Pinchuk – neurologist, Republican Scientific and Practical Centre of Neurology and Neurosurgery;
M.A. Kruglikova – neurologist, Republican Scientific and Practical Centre of Neurology and Neurosurgery;
E.G. Kordzakhia – neonatologist, the 5th City Clinical Hospital.
