DOI: https://doi.org/10.22263/2312-4156.2024.1.15
O.M. Khishova, I.A. Savkov
Modern assortment of excipients for obtaining film coatings of tablets
Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
Vestnik VGMU. 2024;23(1):15-24.
Abstract.
The article presents summarized literature data on film formers used in the composition of tablets film coatings. It has been shown that water-soluble, gastric juice-soluble, intestinal fluids-soluble and insoluble film-forming agents can be used in film tablet coatings. Data analysis of film formers and other auxiliary substances in the composition of film tablet coatings has been carried out. Film formers are applied to tablets in the form of solutions in water, ethyl and isopropyl alcohol, acetone or methylene chloride. The application of optimized ready-made systems for producing film tablet coatings has been shown. Their use makes it possible to reduce the time of obtaining a coating and to increase its microbiological purity. Various auxiliary substances are used in the composition of film tablet coatings: plasticizers that improve their elasticity, dyes for producing colored films, etc.
Keywords: film formers, tablets, film coatings, plasticizers, dyes, pigments.
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Information about authors:
O.M. Khishova – Doctor of Pharmaceutical Sciences, professor, head of the Chair of Pharmaceutical Technologies with the course of the Faculty for Advanced Training & Retraining, Vitebsk State Order of Peoples’ Friendship Medical University, https://orcid.org/0000-0002-9206-5391,
e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Olga M. Khishova;
I.A. Savkov – Master of Pharmaceutical Sciences, senior lecturer of the Chair of Pharmaceutical Technologies with the course of the Faculty for Advanced Training & Retraining, Vitebsk State Order of Peoples’ Friendship Medical University.
