DOI: https://doi.org/10.22263/2312-4156.2024.1.88
D.I. Haurylenka1, E.V. Rodina1, N.I. Korzhenevskaya1, M.Yu. Zhandarov1, E.A. Svistunova1, E.M. Zhandarova2
Infective fungal endocarditis in a kidney transplant recipient: clinical case
1Republican Research Center for Radiation Medicine and Human Ecology, Gomel, Republic of Belarus
2Gomel State Medical University, Gomel, Republic of Belarus
Vestnik VGMU. 2024;23(1):88-95.
Abstract.
The most common fungi which cause endocarditis are species of the genus Candida, usually isolated from surgically removed emboli or resected valves. In this article a case of prosthetic valve endocarditis in a renal transplant patient on immunosuppressive medications is presented. Endocarditis caused by Candida albicans, was managed with a second-generation azole – voriconazole, which was prescribed based on the drug sensitivity and resistance determined. Delay in antifungal therapy is fraught with disease progression and a fatal outcome. Prosthetic mitral valve damage had a relatively positive dynamics, despite an embolic episode. The difficulty in managing the patient was his comorbidity, the development of an adverse event in the form of eosinophilia against the background of the initial empirical antibacterial therapy.
Keywords: fungal endocarditis, septic embolism, vegetations, drug-induced eosinophilia.
References
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Information about authors:
D.I. Haurylenka – Candidate of Medical Sciences, head of the functional diagnostic department, Republican Research Centre for Radiation Medicine and Human Ecology, https://orcid.org/0000-0001-7496-6164,
e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Dzmitry I. Haurylenka;
E.V. Rodina – Candidate of Medical Sciences, functional diagnostic doctor of the functional diagnostic department, Republican Research Centre for Radiation Medicine and Human Ecology;
N.I. Korzhenevskaya – functional diagnostic doctor of the functional diagnostic department, Republican Research Centre for Radiation Medicine and Human Ecology;
M.Yu. Zhandarov – pathologist of the laboratory of cell technologies, Republican Research Centre for Radiation Medicine and Human Ecology, https://orcid.org/0000-0002-3123-9263
E.А. Svistunova – nephrologist of the department of immunopathology and allergology, Republican Research Centre for Radiation Medicine and Human Ecology;
Е.М. Zhandarova – lecturer of the Chair of Internal Diseases No.1 with the courses of Endocrinology and Hematology, Gomel State Medical University, https://orcid.org/0000-0002-0587-6832
