DOI: https://doi.org/10.22263/2312-4156.2024.3.47
M.N. Tillyashaykhov1,2, N.Kh. Rajabova3, N.D. Suyunov3, S.M. Djanklich1
Determining the specific activity of medical hemostatic foam based on aluminum chloride
1Republican Specialized Scientific-Practical Medical Center of Oncology and Radiology, Tashkent, Uzbekistan
2Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan
3Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan
Vestnik VGMU. 2024;23(3):47-55.
Abstract.
Objectives. To study the main indicators of the incidence of oncological diseases, including lung and bronchial cancer, and to determine their prognosis in the Republic of Uzbekistan.
Material and methods. The research materials were the main statistical indicators on cancer, including malignant neoplasms of the bronchi and lung in the Republic of Uzbekistan for the period 2010-2022. The research methods used were mathematical statistics, graphical method, method of simple small squares, trends, multifactor mathematical modeling, systematization of nonlinear processes in medicine in software methods and reasoning methods.
Results. Having studied the epidemiology of cancer for 2010–2022, we can assume that the absolute number of newly diagnosed patients in the forecast for 2026 will be 28,609 cases; the incidence rate per 100,000 population is 75.4, the absolute number of lethal outcomes is 17,037 people. The mortality rate was found to be 44.9 patients per 100,000 population. At the end of the estimated reporting year, the indicators for 2026 are: the absolute number of patients will be 141,641 people, and the morbidity rate per 100,000 population will be 373.5 people. By 2026, the number of permanent residents of the Republic of Uzbekistan is expected to be 37 million 916 people.
According to the results of an analysis of the epidemiology of lung and bronchial cancer for 2011–2022, it was established that the forecast for the absolute number of newly diagnosed patients in 2026 will be 1,816 people, this figure will be 4.8 persons per 100,000 inhabitants, and at the end of the reporting period – 3,107 people, also the incidence rate per 100,000 population is 8.2, the predicted absolute number of lethal outcomes will make up 1,429 people. It has been established that the morbidity forecast rate will be 3.8 patients per 100,000 population.
Conclusions. Based on the above, we can conclude that oncological diseases, including lung and bronchial cancer, tend to incidence increase in the Republic of Uzbekistan, thanks to improved detection by primary care medical workers, improving diagnostic and treatment standards. The reason for this growth is also the increase in the number of permanent residents of the Republic of Uzbekistan.
Keywords: oncological diseases, lung and bronchial cancer, epidemiology, morbidity, statistics, disease prevalence, prognosis.
References
1. Shneyder OV, Kamilova TA, Golota AS, Sarana AM, Shcherbak SG. Biomarkers and targeting therapy in lung cancer. Fiz Reabilitats Meditsina Med Reabilitatsiya. 2021;3(1):74-94. (In Russ.). doi: http://dx.doi.org/10.36425/rehab63268
2. Mukhambetzhan AZh, Urazaeva ST, Urazaev ON, Tusupkalieva KSh, Begalin TB, Amanshieva AA, i dr. Current views on the epidemiology and risk factors of lung cancer. Obzor literatury. Nauka Zdravookhranenie. 2020;22(2):27-37. (In Russ.). doi: http://dx.doi.org/10.34689/SH.2020.22.2.003
3. Tillyashaykhov MN, Ibragimov ShN, Dzhanklich SM. Oncologic service of the Republic of Uzbekistan: analysis of morbidity and mortality rates. Onkol Zhurn. 2021;15(2):74-80. (In Russ.)
4. Petrova NG, Krotov KYu, Vcherashniy DB. Dynamics and prognosis of morbidity and mortality from prostate cancer in St. Petersburg. Uchen Zap SPbGMU im akad IP Pavlova. 2015;22(3):25-8. (In Russ.). doi: http://dx.doi.org/10.24884/1607-4181-2015-22-3-25-28
5. Tillyashaykhov MN, red. Standards for diagnosis and treatment of cancer patients. Tashkent, Uzbekistan; 2021. 257 р. (In Russ.)
6. Byakhova MM, Minakov SN, Frank GA. Lung cancer incidence in the Moscow region (1998-2018). Pul’monologiya. 2020;30(4):401-7. (In Russ.). doi: http://dx.doi.org/10.18093/0869-0189-2020-30-4-401-407
7. Alimov EL, Suyunov ND, Zaynutdinov KhS. Forecast of consumption of medicines used in the treatment of bronchial asthma. Farmatsevt Zhurn. 2005;(1):8-10. (In Russ.)
8. Razhabova NKh, Suyunov ND. Analysis of antineoplastic drugs registered in the Republic of Uzbekistan. Farmatsev Zhurn. 2020;(4):3-10. (In Russ.)
9. Razhabova NKh, Suyunov ND. Analyzing the range of drugs used in the treatment of lung cancer. Farmatsevt Zhurn. 2021;(4):5-17. (In Russ.)
10. Razhabova NKh, Suyunov ND. Retrospective analysis of medical records of lung cancer patients. Farmatsevt Zhurn. 2022;(6):21-30. (In Russ.)
11. Suyunov ND, Razhabova NKh. Effectiveness indicators of drugs used in squamous cell lung cancer. Farmatsiya. 2023;(1):36-48. (In Russ.). doi: http://dx.doi.org/10.29296/25419218-2023-01-06
12. Wooldridge JM. Introductory Introductory Econometrics: A Modern Approach (MindTap Course List). 7th ed. Cengage Learning; 2019. 816 р.
13. Stock JH, Watson MW. Introduction to Econometrics. 4th еd. United Kingdom; 2020. 801 р.
Submitted 10.04.2024
Accepted 14.06.2024
Information about authors:
M.N. Tillyashaykhov – Doctor of Medical Sciences, professor, director of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology of the Republic of Uzbekistan; head of the Chair of Oncology, Oncohematology and Radiation Oncology, Tashkent Pediatric Medical Institute, https://orcid.org/0000-0001-6878-011X
N.Kh. Rajabova – Doctor of Philosophy (PhD) in Pharmaceutical Sciences, lecturer of the Chair of Pharmaceutical Business Organization, Tashkent Pharmaceutical Institute. https://orcid.org/0000-0003-2237-150X
N.D. Suyunov – Doctor of Sciences (Pharmaceutics), professor of the Chair of Pharmaceutical Business Organization, Tashkent Pharmaceutical Institute, https://orcid.org/0000-0002-2712-958X
e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Nizom D. Suyunov;
S.M. Dzhanklich – Candidate of Medical Sciences, doctor of Cancer Prevention Center, Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology of the Ministry of Health of the Republic of Uzbekistan, https://orcid.org/0000-0001-9881-4149
