DOI: https://doi.org/10.22263/2312-4156.2024.3.79
M.S. Nedoseikina1, A.V. Mishin1, A.N. Tugarinova2, G.V. Voronovich2
Capillary placental hemangioma (clinical case)
1Gomel State Medical University, Gomel, Republic of Belarus
2Gomel Regional Clinical Hospital, Gomel, Republic of Belarus
Vestnik VGMU. 2024;23(3):79-87.
Abstract.
Tumors of the placenta are a rather rare occurrence in the practice of an obstetrician-gynecologist, especially neoplasia from chorionic mesenchyme. Most clinical guidelines do not contain algorithms for the diagnosis and management of pregnancy with nontrophoblastic tumors. The purpose of the study was to describe the clinical manifestations of large chorioangioma and to compare the symptoms and chosen tactics with those cases, that were published in the scientific journals. A clinical case is described with a detailed analysis of diagnosing and treatment tactics. The tumor and placenta histological examination was performed using standard methods. Scientific articles on the PICO-strategy of research according to keywords were selected for comparison. Both in our case and in previously published cases, there is a relationship between the severity of clinical symptoms and the size of the tumor and the intensity of its growth. Actively growing large chorioangiomas are associated with acute polyhydramnios, intrauterine hypoxia, postnatal anemia in a newborn and adverse perinatal outcome.
Keywords: chorioangioma, perinatal outcome, maternal outcome, diagnosis, delivery.
Conflict of interest. The authors declare that there is no obvious or potential conflict of interest, connected with the publication of the article and also confirm the fact of familiarizing the patient with the text of the article prior to submitting it for printing.
Acknowledgments. The authors express their gratitude to the patient, who favorably treated their request to publish a scientific description of the clinical case encountered by her, as well as to experts and editors of the edition while working with their article.
References
1. Fan M, Skupski DW. Placental chorioangioma: literature review. J Perinat Med. 2014 May;42(3):273-9. doi: http://dx.doi.org/10.1515/jpm-2013-0170
2. Shelaeva EV, Prokhorova VS, Nagorneva SV. Placental chorionangiomas: diagnosis and treatment tactics. Zhurn Akusherstva Zhenskikh Boleznei. 2017;66(3):124-34. (In Russ.). doi: http://dx.doi.org/10.17816/JOWD663124-134
3. Asokan S, Chadalavada K, Gardi R, Sastry V. Prenatal diagnosis of placental tumor by ultrasound. J Clin Ultrasound. 1978 Jun;6(3):180-1. doi: http://dx.doi.org/10.1002/jcu.1870060314
4. Zanardini C, Papageorghiou A, Bhide A, Thilaganathan B. Giant placental chorioangioma : natural history and pregnancy outcome. Ultrasound Obstet Gynecol. 2010 Mar;35(3):332-6. doi: http://dx.doi.org/10.1002/uog.7451
5. Passalacqua G, Donati L, Ferretti M, Giovannini G, Sbaraglia M, Clerici G. Cellular placental chorioangioma and adverse fetal outcome. J Clin Gynecol Obstet. 2014 May;3(2):73-5. doi: http://dx.doi.org/10.14740/jcgo242w
6. Dmitrieva SL, Dvoryanskiy SA. Placental chorionangioma (clinical case). Vyat Med Vestn. 2022;(3):93-6. (In Russ.). doi: http://dx.doi.org/10.24412/2220-7880-2022-3-93-96
Submitted 01.04.2024
Accepted 14.06.2024
Information about authors:
M.S. Nedoseikina – Candidate of Medical Sciences, associate professor of the Chair of Obstertrics and Gynecology with the course of the Faculty for Advanced Training & Retraining, Gomel State Medical University; obstertrician-gynecologist of the highest qualification category, http://orcid.org/0000-0002-8366-9409
e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Marina S. Nedoseikina;
A.V. Mishin – senior lecturer of the Chair of Pathological Anatomy, Gomel State Medical University, http://orcid.org/0000-0003-1247-9015
A.N. Tugarinova – head of the maternity department, obstertrician-gynecologist of the 1st qualification category, Gomel Regional Clinical Hospital, http://orcid.org/0009-0002-3434-295X
G.V. Voronovich – deputy chief physician for childhood and obstetrics, obstertrician-gynecologist of the highest qualification category, Gomel Regional Clinical Hospital, http://orcid.org/0009-0007-8112-1777
