DOI: https://doi.org/10.22263/2312-4156.2024.6.96
P.E. Vankovich, O.P. Kezlya
Metabolic therapy effects on the blood acid-base status and gas transport function in patients with diaphyseal fractures of the tibia bones
Belarusian State Medical University, Minsk, Republic of Belarus
Vestnik VGMU. 2024;23(6):96-105.
Abstract.
This article presents the study results of the gas transport function and acid-base state of the blood in 110 patients with diaphyseal fractures of the shin bones under the use of metabolic therapy. All patients were divided into 3 study groups. The comparison group consisted of 45 people to whom the standard treatment tactics in the early postoperative period was applied. The main group included 65 individuals, in whom the standard treatment tactics were supplemented by the complex of antioxidant therapy (intravenous infusions of cytoflavin No. 10-15) and hyperbaric oxygen therapy (sessions of 55 min at 1.0-1.8 ATA, No. 10-15). To conduct the comparative assessment of the studied parameters with the normal level, 30 practically healthy individuals were examined, who formed the control group. Metabolic therapy led to the correction of metabolic acidosis, gas transport function of the blood and normalization of the acid-base balance of the blood, which testifies to the stimulation of reparative osteogenesis in the fracture zone. The treatment results were studied in all 110 (100%) patients over the period of 24 months.
Keywords: hyperbaric oxygen therapy, antioxidant therapy, fractures, shin, gas transport function, acid-base state.
The study was performed as the program target – 3.57 State Scientific Research Programs “Translational medicine”, subprogram “Innovative technologies in clinical medicine” on the funded subject “To work out the stimulation method of the reparative regeneration in the fracture zone region by introducing metabolic therapy in treatment complex”.
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Submitted 06.11.2024
Accepted 04.12.2024
Information about authors:
P.E. Vankovich – senior lecturer of the Chair of Traumatology and Orthopedics, Belarusian Medical Academy of Postgraduate Education;
e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Pavel E. Vankovich;
O.P. Kezlya – Doctor of Medical Sciences, professor of the Chair of Traumatology and Orthopedics, Belarusian Medical Academy of Postgraduate Education.
