DOI: https://doi.org/10.22263/2312-4156.2025.4.49
D.S. Schelkunov1, K.M. Kubrakov1, V.P. Semenov1, E.A. Matusevich2
Method of treatment of nosocomial sinusitis in patients of intensive care units
1Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
2Vitebsk Regional Clinical Hospital, Vitebsk, Republic of Belarus
Vestnik VGMU. 2025;24(4):49-56.
Abstract.
The clinical significance of nosocomial sinusitis (NS) is in its association with an increase in infectious complications such as ventilator-associated pneumonia (VAP), sinus thrombosis, sepsis, etc. Due to the difficult outflow of the contents of the paranasal sinuses and high antibiotic resistance of NS pathogens, the use of local treatment methods such as drainage is rather relevant.
Objectives. To develop an effective method for drainage of the maxillary sinuses (MS) in NS for patients of the intensive care unit (ICU).
Material and methods. An open, prospective, non-randomized study was performed. Patients were in the ICU and divided into 2 groups: Group 1 – 28 patients with NS on the mechanical ventilation (MV) and treated according to the method we have developed; Group 2 – 26 patients, in whom the treatment of NS was carried out by the standard method – the maxillary sinus puncture.
Results. While comparing two groups, significantly lower total time was established for the sanitation of the maxillary sinus (number of procedures n=2) in patients of group 1 (pMann–Whitney U test<0.05). Also, during repeated manipulations for the sanitation of the maxillary sinus in patients of group 1, there was no pain reaction from the procedure and there was no need to use local anesthetics. Nasal bleeding from during manipulations in patients of group 1 was observed in 2 cases, while in group 2 – in 8 cases respectively.
Conclusions. The developed method of maxillary sinus drainage, which includes the installation of a double-lumen catheter into the maxillary sinus cavity with subsequent daily rinsing of the sinus with 0.05% chlorhexidine bigluconate solution, is more effective and safer both in terms of time spent on the procedure (pMann–Whitney U test<0.05) and the number of bleedings (p=0.0255), compared to the standard method of the maxillary sinus puncture.
Keywords: sinusitis, sinus drainage, puncture, nosocomial infection.
References
1. Arens JF, Lejeune FE, Webre DR. Maxillary sinusitis, a complication of nasotracheal intubation. Anesthesiology. 1974 Apr;40(4):415-416. doi: http://dx.doi.org/10.1097/00000542-197404000-00024
2. Caplan ES, Hoyt N. Nosocomial sinusitis. JAMA. 1982 Feb;247(5):639-641.
3. Shchelkunov DS, Semenov VM, Kubrakov KM. Treatment of nosocomial sinusitis in neurosurgical patients. Otorinolaringologiya Vostochnaya Evropa. 2023;13(2 elektron pril). URL: https://recipe.by/wp-content/uploads/woocommerce_uploads/2023/06/Tezisy_Prilozhenie-k-Otorino_2-2023.pdf [Accessed 14th August 2025]. (In Russ.).
4. Rouby JJ, Laurent P, Gosnach M, Cambau E, Lamas G, Zouaoui A, et al. Risk factors and clinicalrelevanceof nosocomial maxillary sinusitis in the critically ill. American Journal of Respiratory and Critical Care Medicine. 1994 Sep;150(3):776-83. doi: http://dx.doi.org/10.1164/ajrccm.150.3.8087352
5. Holzapfel L, Chevret S, Madinier G, Ohen F, Demingeon G, Coupry A, et al. Influence of long-termoroornasotracheal intubation on nosocomial maxillary sinusitis and pneumonia:results of a prospective, randomized, clinicaltrial. Critical Care Medicine. 1993 Aug;21(8):1132-1138. doi: http://dx.doi.org/10.1097/00003246-199308000-00010
6. Deutschman CS, Wilton P, Sinow J, Dibbell DJr, Konstantinides FN, Cerra FB. Paranasal sinusitis associated with nasotracheal intubation: a frequently unrecognized and treatable source of sepsis. Critical Care Medicine. 1986 Feb;14(2):111-114.
7. Heffner JE. Nosocomial sinusitis. Den of multiresistant thieves? American Journal of Respiratory and Critical Care Medicine. 1994 Sep;150(3):608-609. doi: http://dx.doi.org/10.1164/ajrccm.150.3.8087325
8. Geiss NK. Nosocomial sinusitis. Intensive Care Medicine. 1999 Oct;25(10):1037-1039. doi: http://dx.doi.org/10.1007/s001340051009
9. Lazareva LA, Saydulaev SA, Reznikov RV. Diagnostic algorithm and treatment tactics for nosocomial rhinosinusitis in the intensive care unit of a large multidisciplinary hospital. Rossiiskaya Otorinolaringologiya. 2013;64(3):104-109. (In Russ.).
10. Palchun VT, red. Othorinolaryngology. National leadership. Moscow, RF: GEOTAR-Media; 2008. 261 р.
11. Miroshnichenko AP, Stepanov EN; Samar gos med un-t, zayavitel'. Poleznaya model' RU 144275 U1, MPK A61B 17/00 (2006.01). Needle for puncture of maxillary sinus Miroshnichenko-Stepanova: № 2014112112/14: zayavleno 28.03.2014: opubl 20.08.2014. Izobreteniya Poleznye modeli. 2014;(23). (In Russ.).
12. Kryukov AI, Aleksanyan TA, Tovmasyan AS, Levina SV, Agliullin TA, Bolgar AYa, Kishinevskiy AE, Agliullin AF; Nauch-issled klin in-t otorinolaringologii im LI Sverzhevskogo, zayavitel'. Poleznaya model' RU 2786328 S1, MPK A61B 17/24 (2006.01), A61B 17/34 (2006.01), A61M 25/00 (2006.01). Device and method of maxillary sinus drainage: № 2022106328: zayavleno 11.03.2022: opubl 20.12.2022. Izobreteniya Poleznye modeli. 2022;(35). (In Russ.).
13. Shchelkunov DS, Semenov VM, Kubrakov KM, Kornilov AV; Viteb gos med un-t, zayavitel'. Patent BY 13322, A 61B 17/24 (2006.01), A 61K 17/34 (2006.01), A 61M 25/00 (2006.01). Antral dilator: № u 20230081; zayavleno 14.04.2023; opubl 30.10.2023. 4 р. (In Russ.).
Submitted 07.07.2025
Accepted 22.08.2025
Information about authors:
Dmitry S. Schelkunov – senior lecturer of the Chair of Ophthalmology & Otorhinolaryngology, Vitebsk State Order of Peoples’ Friendship Medical University, e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.;
K.M. Kubrakou – Doctor of Medical Sciences, associate professor, professor of the Chair of Neurology & Neurosurgery, Vitebsk State Order of Peoples’ Friendship Medical University;
V.M. Semenov – Doctor of Medical Sciences, professor, head of the Chair of Infectious Diseases with the course of the Faculty for Advanced Training & Retraining, Vitebsk State Order of Peoples’ Friendship Medical University;
E.A. Matusevich – Candidate of Medical Sciences, chief physician of Vitebsk Regional Clinical Hospital.