DOI: https://doi.org/10.22263/2312-4156.2026.2.33
Y.O. Ryabchikova1, Y.G. Shanko2
Chronic subdural hematoma: current state of the problem
1Vitebsk Regional Clinical Hospital, Vitebsk, Republic of Belarus
25th City Clinical Hospital, Minsk, Republic of Belarus
Vestnik VGMU. 2026;25(2):33-42.
Abstract.
Chronic subdural hematoma (CSDH) is one of the most common neurosurgical conditions in elderly patients. Its increasing incidence is due to the aging of the population, the high prevalence of traumatic brain injury, and the increasing number of patients receiving long-term anticoagulant and antiplatelet therapy. The clinical manifestations of CSDH are variable and nonspecific, often have a long latency period, and can mimic other central nervous system diseases, complicating timely diagnosis.
This article presents a current review of the literature on the epidemiology, pathophysiology, clinical presentation, diagnosis, and treatment of chronic subdural hematoma. Particular attention is paid to neuroimaging techniques, such as computed tomography and magnetic resonance imaging, as well as morphological classifications of chronic subdural hematoma, including the Nakaguchi classification and its modifications, which have prognostic significance.
Current approaches to the treatment of CSDH are reviewed, including dynamic observation, surgical hematoma drainage using various drainage options, and the role of adjuvant and alternative treatments. The indications and limitations of corticosteroids, drug therapy, and endovascular embolization of the middle meningeal artery are analyzed.
This review reflects current trends in the diagnosis and treatment of CSDH and highlights the need for further high-quality clinical research to develop standardized recommendations.
Keywords: chronic subdural hematoma, computed tomography, Nakaguchi classification, hematoma capsule, surgical treatment, risk factors for recurrence, conservative treatment, prognosis.
References
1. Stubbs DJ, Davies BM, Edlmann E, Ansari A, Bashford TH, Braude P, et al. Clinical practice guidelines for the care of patients with a chronic subdural haematoma: multidisciplinary recommendations from presentation to recovery. British Journal of Neurosurgery. 2026 Feb;40(1):94-103. doi: http://dx.doi.org/10.1080/02688697.2024.2413445
2. Potapov AA, Likhterman LB. Kravchuk AD. Chronic subdural hematomas. Moscow, RF: Antidor; 1997. 230 p. (In Russ.).
3. Zolfaghari Sh, Bartek JJr, Strom I, Djärf F, Wong SS, Ståhl N, et al. Burr hole craniostomy versus minicraniotomy in chronic subdural hematoma: a comparative cohort study. Acta Neurochirurgica. 2021 Nov;163(11):3217-3223. doi: http://dx.doi.org/10.1007/s00701-021-04902-3
4. Markwalder T, Seilor R. Chronic subdural hematoma: to drain or not drain? Neurosurgery. 1985 Feb;16(2):185-188. doi: http://dx.doi.org/10.1227/00006123-198502000-00010
5. Konovalov AN, Kravchuk AD, Potapov AA, Likhterman LB, El-Kadi M, Zakharova ME. Minimally invasive chronic subdural hematoma surgery. V: Konovalov AN, Potapov AA, Likhterman LB, Kornienko VN, Kravchuk AD, Okhlopkov VA, i dr. Rekonstruktivnaya i minimal’no invazivnaya khirurgiya posledstvii cherepno-mozgovoi travmy. Moscow, RF; 2012. Р. 226–283. (In Russ.).
6. Landriel Ibanez FA, Hem S, Ajler P, Vecchi E, Ciraolo C, Baccanelli M, et al. A new classification of complications in neurosurgery. World Neurosurgery. 2011 May-Jun;75(5-6):709-715. doi: http://dx.doi.org/10.1016/j.wneu.2010.11.010
7. Feghali J, Yang W, Huang J. Updates in Chronic Subdural Hematoma: Epidemiology, Etiology, Pathogenesis, Treatment and Outcome. World Neurosurgery. 2020 Sep:141:339-345. doi: http://dx.doi.org/10.1016/j.wneu.2020.06.140
8. Stubbs DJ, Vivian ME, Davies BM, Ercole A, Burnstein R, Joannides AJ. Incidence of chronic subdural haematoma: a single-centre exploration of the effects of an ageing population with a review of the literature. Acta Neurochir. 2021 Sep;163(9):2629-2637. doi: http://dx.doi.org/10.1007/s00701-021-04879-z
9. Neifert SN, Chaman EK, Hardigan T, Ladner TR, Feng R, Caridi JM, et al. Increases in subdural hematoma with an aging population–the future of American cerebrovascular disease. World Neurosurg. 2020 Sep:141:e166-e174. doi: http://dx.doi.org/10.1016/j.wneu.2020.05.060
10. Brennan PM, Kolias AG, Joannides AJ, Shapey J, Marcus HJ, Gregson BA, et al. The management and outcome for patients with chronic subdural hematoma: a prospective, multicenter, observational cohort study in the United Kingdom. Journal of Neurosurgery. 2017 Oct;127(4):732-739. doi: http://dx.doi.org/10.3171/2016.8.JNS16134
11. Stubbs DJ, Davies BM, Dixon-Woods M, Bashford TH, Braude P, Bulters D, et al. Protocol for the development of a multidisciplinary clinical practice guideline for the care of patients with chronic subdural haematoma. Wellcome Open Research. 2023 Sep:8:390. doi: http://dx.doi.org/10.12688/wellcomeopenres.18478.1
12. Gelabert-Gonzalez M, Iglesias-Pais M, Garcia-Allut A, Martinez-Rumbo R. Chronic subdural haematoma: surgical treatment and outcome in 1000 cases. Clinical Neurology and Neurosurgery. 2005 Apr;107(3):223-229. doi: http://dx.doi.org/10.1016/j.clineuro.2004.09.015
13. Kolias AG, Chari A, Santarius T, Hutchinso PJ. Chronic subdural haematoma: modern management and emerging therapies. Nature Reviews Neurology. 2014 Oct;10(10):570-578. doi: http://dx.doi.org/10.1038/nrneurol.2014.163
14. Likhterman LB, Kravchuk AD, Okhlopkov VA. Chronic subdural hematomas of the brain: problems and solutions. Part 1. Clinical variants and diagnostics. Neurology. 2021;2:21-27. doi: http://dx.doi.org/10.47407/kr2021.2.2.00038. (In Russ.).
15. Nakaguchi H, Tanishima T, Yoshimasu N. Factors in the natural history of chronic subdural hematomas that influence their postoperative recurrence. Journal of Neurosurgery. 2001 Aug;95(2):256-262. doi: http://dx.doi.org/10.3171/jns.2001.95.2.0256
16. Zhang JY, Wang S, Foo ASC, Yang M, Quah BL, Sun IS, et al. Outcomes of Subdural Versus Subperiosteal Drain After Burr-Hole Evacuation of Chronic Subdural Hematoma: A Multicenter Cohort Study. World Neurosurgery. 2019 Nov:131:e392-e401. doi: http://dx.doi.org/10.1016/j.wneu.2019.07.168
17. Takei J, Hirotsu T, Hatano K, Ishibashi T, Inomata T, Noda Y, et al. Modified computed tomography classification for chronic subdural hematoma features good interrater agreement. World Neurosurgery. 2021 Jul:151:e407-e417. doi: http://dx.doi.org/10.1016/j.wneu.2021.04.052
18. Miah IP, Tank Y, Rosendaal F, Peul WC, Dammers R, Lingsma HF, et al. Radiological prognostic factors of chronic subdural hematoma recurrence: a systematic review and meta-analysis. Neuroradiology. 2021 Jan;63(1):27-40. doi: http://dx.doi.org/10.1007/s00234-020-02558-x
19. Potapov AA, Likhterman LB, Gavrilov AG. Recommendations for the diagnosis and treatment of patients with traumatic brain injury from evidence-based medicine. Communication I. Evidence-based medicine technologies. Voprosy Neirokhirurgii imeni NN Burdenko. 2005;(3):3-8. (In Russ.).
20. Hani L, Vulcu S, Branca M, Fung C, Z'Graggen WJ, Murek M, et al. Subdural versus subgaleal drainage for chronic subdural hematomas: a post hoc analysis of the TOSCAN trial. Journal of Neurosurgery. 2019 Aug;133(4):1147-1155. doi: http://dx.doi.org/10.3171/2019.5.JNS19858
21. Shi M, Xiao LF, Zhang TB, Tang QW, Zhao WY. Adjuvant corticosteroids with surgery for chronic subdural hematoma: a systematic review and meta-analysis. Frontiers in Neuroscience. 2021 Dec:15:786513. doi: http://dx.doi.org/10.3389/fnins.2021.786513
22. Shrestha DB, Budhathoki P, Sedhai YR, Jain S, Karki P, Jha P, et al. Steroid in Chronic Subdural Hematoma: An Updated Systematic Review and Meta-Analysis Post DEX-CSDH Trial. World Neurosurg. 2022 Feb:158:84-99. doi: http://dx.doi.org/10.1016/j.wneu.2021.10.167
23. Hutchinson PJ, Edlmann E, Bulters D, Zolnourian A, Holton P, Suttner N, et al. Trial of Dexamethasone for Chronic Subdural Hematoma. New England Journal of Medicine. 2020 Dec;383(27):2616-2627. doi: http://dx.doi.org/10.1056/NEJMoa2020473
24. Kolias AG, Chari A, Santarius T, Hutchinson PJ. Chronic subdural haematoma: modern management and emerging therapies. Nature Reviews Neurology. 2014 Oct;10(10):570-8. doi: http://dx.doi.org/10.1038/nrneurol.2014.163
25. Ban SP, Hwang G, Byoun HS, Kim T, Lee SU, Bang JS, et al. Middle meningeal artery embolization for chronic subdural hematoma. Radiology. 2018 Mar;286(3):992-999. doi: http://dx.doi.org/10.1148/radiol.2017170053
26. Jindal G, Sharafaddin-Zadeh Y, Bukhari O, Goyal M, Ospel JM. Complications of middle meningeal artery embolization for chronic subdural hematoma: a systematic literature review. Canadian Journal of Neurological Sciences. 2025 Jul:1-11. doi: http://dx.doi.org/10.1017/cjn.2025.10369
27. On the approval of the Instructions on the procedure for providing medical care to patients with a brain injury: prikaz M-va zdravookhraneniya Resp Belarus' ot 24 sent 2012 g № 1110. ETALON : inform-poiskovaya sistema [Accessed 09th April 2026]. (In Russ.).
28. Min X, Pin C, Xun Z, Wang C, Shi X, Yu B. Effects of atorvastatin on conservative and surgical treatments of chronic subdural hematoma in patients. World Neurosurg. 2016 Jul:91:23-28. doi: http://dx.doi.org/10.1016/j.wneu.2016.03.067
29. Wang D, Li T, Tian Y, Wang S, Jin C, Wei H, et al. Effects of atorvastatin on chronic subdural hematoma: a preliminary report from three medical centers. Journal of the Neurological Sciences. 2014 Jan;336(1-2):237-242. doi: http://dx.doi.org/10.1016/j.jns.2013.11.005
30. Weigel R, Schilling L, Schmiedek P. Specific pattern of growth factor distribution in chronic subdural hematoma (CSH): evidence for an angiogenic disease. Acta Neurochirurgica. 2001 Aug;143:811-818. doi: http://dx.doi.org/10.1007/s007010170035
31. Kravtchouk AD, Likhterman LB, Potapov AA, El-Kadi H. Postoperative Complications of Chronic Subdural Hematomas: Prevention and Treatment. Neurosurgery Clinics of North America. 2000 Jul;11(3):547-552.
Submitted 16.03.2026
Accepted 14.04.2026
Information about authors:
Yulia O. Ryabchikova – neurosurgeon of the Neurosurgical Department, Vitebsk Regional Clinical Hospital, post-graduate of the Republican Scientific and Practical Centre of Neurology and Neurosurgery, e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.;
Y.G. Shanko – Doctor of Medical Sciences, professor, corresponding member of NAS of Belarus, head of the Department of Neurology and Neurosurgery, 5th City Clinical Hospital, Minsk.

