2026-4-N.A. Shedko, А.V. Marochkov, U.A. Dudko, V.A. Livinskaya

DOI: https://doi.org/10.22263/2312-4156.2026.4.47

N.A. Shedko¹, А.V. Marochkov ^1,2, U.A. Dudko^1,2, V.A. Livinskaya³
Component infusion-transfusion therapy in anesthesia management for ascending aortic surgeries
¹Mogilev Regional Clinical Hospital, Mogilev, Republic of Belarus
²Vitebsk State Order of Peoples' Friendship Medical University, Vitebsk, Republic of Belarus
³Belarusian-Russian University, Mogilev, Republic of Belarus

Vestnik VGMU. 2026;25(4):47-53.

Abstract.
Objectives. To determine the optimal volume of infusion-transfusion therapy (ITT) in patients undergoing anesthesia for ascending aortic and aortic arch surgery. Material and methods. We analyzed 43 cases of providing medical care to patients with acute ascending aortic and aortic arch dissection (type A). We divided patients into three groups based on intraoperative blood loss: the first group included patients with intraoperative blood loss of up to 30% of the circulating blood volume (CBV), the second group – with intraoperative blood loss of 31-70%, and the third group – with blood loss more than 70%. Results: In-hospital mortality in group 1 (n=10) was 40%, in group 2 (n=26) – 30.8%, in group 3 (n=7) – 71.4%. The volume 48 of ITT in group 1 was 2068 (1260; 2720) ml, in group 2 – 3665 (2960; 4030) ml, in group 3 – 5420 (4160; 6120) ml (p<0.05). The ratio of transfusion therapy (TT) components (erythrocyte blood components: fresh frozen plasma: cryoprecipitate: platelet blood component) in group 1 was 1:1:4:2.5, in group 2 – 1:1:2.5:1.5, in group 3 – the ratio was 1:0.75:1.5:0.8. Conclusions. The analysis of the quantity and quality of ITT as a component of anesthetic management during surgeries on the ascending aorta and aortic arch was conducted, which allows improving the treatment outcomes for this pathology.

Keywords: anesthesia, blood loss, ascending aortic dissection, infusion therapy, transfusion therapy.

References

1. Ostrovskiy YuP. Cardiac surgery. Moscow, RF: Meditsinskaya literatura; 2007. 559 р. (In Russ.).
2. Redkoborodyy AV, Selyaev VS, Rubtsov NV, Kokov LS, Muslimov RSh, Popova IE, i dr. Selection of surgical treatment tactics for the "acute" stratification of aorta I type by De Bakey in conditions of a multidisciplinary surgical hospital. Zhurnal imeni NV Sklifosovskogo «Neotlozhnaya meditsinskaya pomoshch'». 2023;12(1):14-22. (In Russ.). doi: 10.23934/2223-9022-2023-12-1-14-22
3. Grigoryev EV, Lebedinskiy KM, Shchegolev AV, Bobovnik SV, Bulanov AYu, Zabolotskikh IB, i dr. Resuscitation of intensive care for acute acute mass bleeding in adult patients. Anesteziologiya i Reanimatologiya. 2020;(1):5-24. (In Russ.). doi: 10.17116/anaesthesiology20200115
4. Bryusov PG. Emergency determination of blood loss by nosegram. Voenno-meditsinskii Zhurnal. 1986;(9):61-62. (In Russ.).
5. Mezhevikina VM, Lazarev VV, Zhirkova YuV. Intraoperative methods of blood loss assessment. Literature review. Rossiiskii Vestnik Detskoi Khirurgii Anesteziologii i Reanimatologii. 2022;12():371-381. (In Russ.). doi: 10.17816/psaic991
6. Silvey G, Khromava M, Vayner M, Augustides DzhG, Kastillo KhG. Anaesthesiologic care for patients with type A aortic dysfunction. Obshchaya Reanimatologiya. 2019;15(2):36-52. (In Russ.). doi: 10.15360/1813-9779-2019-2-36-52
7. Trekova NA, Charchyan ER, Akselrod BA, Seleznev MN, Guskov DA, Solovyeva IN. Modern techniques for preserving patient blood and reducing the use of donor blood during operations on the ascending aorta and aorta arc. Anesteziologiya i Reanimatologiya. 2015;60(5):20-26. (In Russ.).
8. Bodyakov KV, Marochkov AV, Kulik AS, Dudko VA, Lipnitskiy AL. Features of the use of trahenacetic acid in patients with cardiac surgery. Novosti Khirurgii. 2021;(5):590- 597. (In Russ.)
9. Kurashov MS, Marochkov AV, Voronkov PA. Determination of blood flow in cardiac surgery patients by gravimetric method and hemoglobin balance method. Vestnik Vitebskogo Gosudarstvennogo Meditsinskogo Universiteta. 2022;21(6):57-63. (In Russ.).
10. The R Project for Statistical Computing. Vienna, Austria : R Foundation for Statistical Computing, 2024. URL: https:// www.R-project.org/ [Accessed 30th June 2026].
11. Rossaint R, Afshari A, Bouillon B, Cerny V, Cimpoesu D, Curry N, et al. The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition. Critical Care. 2023;27:80. doi: 10.1186/s13054-023- 04327-7
12. Shedko NA, Dudko VA, Lipnitskiy AL, Marochkov AV, Kulik AS. Features of infuso-transfusional therapy in anesthesiological support for thoracic aortic operations. Zhurnal Grodnenskogo Gosudarstvennogo Meditsinskogo Universiteta. 2024;22(6):554-559. (In Russ.).
13. Luzin AV, Bogomolov DV, Baranova MYa, Shakaryants ZhE, Dolzhanskiy OV, Dzivina MI. On the question of determining the type of tanatogenesis and the rate of death in massive blood loss. Problemy Ekspertizy v Meditsine. 2004;04(15-3):14-16. (In Russ.).
14. Holcomb JB, Jenkins D, Rhee P, Johannigman J, Mahoney P, Mehta S, et al. Damage control resuscitation: directly addressing the early coagulopathy of trauma. The Journal of Trauma. 2007 Feb;62(2):307-10. doi: 10.1097/TA.0b013e3180324124

Submitted 31.03.2026
Accepted 27.08.2026

Information about authors:

Natalia A. Shedko– anesthesiologist-resuscitator of the anesthesiology and resuscitation department of the center of cardiovascular surgery, Mogilev Regional Clinical Hospital, https://orcid.org/0009-0001-5005-8724, e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.;
A.V. Marochkov – Doctor of Medical Sciences, professor, anesthesiologist-resuscitator of the anesthesiology and resuscitation department, Mogilev Regional Clinical Hospital; professor of the branch of the Chairs of Anesthesiology & Resuscitation and Hospital Surgery with the course of the Faculty for Advanced Training & Retraining, Vitebsk State Order of Peoples’ Friendship Medical University, https://orcid.org/0000-0001-5092-8315;
V.A. Dudko – anesthesiologist-resuscitator, head of the department of anesthesiology and resuscitation of the center of cardiovascular surgery, Mogilev Regional Clinical Hospital, lecturer of the branch of the Chairs of Anesthesiology and Resuscitation with the course of the Faculty for Advanced Training & Retraining and Hospital Surgery of the Faculty for Advanced Training & Retraining, Vitebsk State Order of Peoples’ Friendship Medical University”, https://orcid.org/0000-0002-5959-5454;
V.A. Livinskaya – Candidate of Physical-mathematical Sciences, associate professor of the Chair of Finance and Accounting, Belarusian-Russian University, https://orcid.org/0000-0001-8953-8533.

Поиск по сайту