Paramonava N.S.1, Karcheuski A.A.1, Vezhal V.V.2, Kryvetski D.S.1
The peculiarities of chronic gastritis course in children with connective tissue dysplasia
1Grodno State Medical University», Grodno, Republic of Belarus
2Grodno Regional Children’s Clinical Hospital, Grodno, Republic of Belarus
Vestnik VGMU. 2017;16(3):21-28.
Changes of the connective tissue structure as a result of its dysplasia play an important role in the development and course of a number of diseases including chronic gastritis.
Objectives. To determine clinical peculiarities of chronic gastritis course in children with connective tissue dysplasia.
Material and methods. 194 children of school age with chronic gastritis were examined. The detection of connective tissue dysplasia was carried out according to T. Milkovska-Dimitrova’s criteria.
Results. Clinical symptoms of chronic gastritis in children accompanied by connective tissue dysplasia are characterized by the early debut of a disease, the long period of hospitalization, the prevalence of intoxication symptoms, marked abdominal pain syndrome, frequent involvement in the pathological process of other organs and systems. In children with pronounced connective tissue dysplasia the high level of Helicobacter pylori (Hp) contamination in the stomach mucous membrane was observed, that reflects the decrease in the immune response to Hp infection.
Conclusions. Connective tissue dysplasia aggravates the course of chronic gastritis in children, which demands deep diagnostic investigations in this category of patients.
Key words: children, chronic gastritis, connective tissue dysplasia.
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Information about authors:
Paramonava N. S. – Doctor of Medical Sciences, head of the Chair of Childhood Diseases No.2, Grodno State Medical University;
Karcheuski A. A. – teacher of the Chair of Childhood Diseases No.2, Grodno State Medical University;
Vezhal V. V. – head of the pediatric department No. 6, Grodno Regional Children’s Clinical Hospital;
Kryvetski D. S. – endoscopist, Grodno Regional Children’s Clinical Hospital.