DOI: https://doi.org/10.22263/2312-4156.2017.4.16
Gusakova E.A., Gorodetskaya I.V.
The effect of iodine-containing thyroid hormones on peripheral stress-limiting factors
Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
Vestnik VGMU. 2017;16(4):16-23.
Abstract.
The study of the patterns of stress development as well as of local factors that prevent or limit the intensity of stress reactions, is an important objective of physiology and medicine. The stimulating effect of iodine-containing thyroid hormones on the activity and content of peripheral components (cyclic adenine nucleotides, prostaglandins, antioxidants, heat shock proteins) of the stress-limiting system has been established. This effect is tissue-specific, depends on the age and sex of animals, as well as on the severity of thyroid dysfunction. The obtained data on the influence of iodine-containing thyroid hormones on the peripheral part of the stress-limiting system will broaden the fundamental ideas about the mechanisms of their action and role in the processes of phenotypic adaptation of the organism.
Key words: iodine-containing thyroid hormones, peripheral stress-limiting system.
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Information about authors:
Gusakova E.A. – Candidate of Biological Sciences, associate professor of the Chair of General, Physical and Colloid Chemistry, Vitebsk State Order of Peoples’ Friendship Medical University;
Gorodetskaya I.V. – Doctor of Medical Sciences, professor, dean of the Medical Faculty, Vitebsk State Order of Peoples’ Friendship Medical University.
Correspondence address: Republic of Belarus, 210023, Vitebsk, 27 Frunze ave., Vitebsk State Order of Peoples’ Friendship Medical University, Medical Faculty. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Irina V. Gorodetskaya.
