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DOI: https://doi.org/10.22263/2312-4156.2017.4.89

Miklis N.I.1, Alekseyev I.S.2, Doroshenko I.A.2
The efficiency of the wound electroformed nonwoven materials on the basis of polyvinyl spirit
1Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
2Vitebsk State Technological University, Vitebsk, Republic of Belarus

Vestnik VGMU. 2017;16(4):89-96.

Abstract.
The purpose of this work was to determine the antimicrobial activity and solubility of the electroformed nonwoven materials from nanodimensional fibers on the basis of polyvinyl spirit. The experimental samples were received by the electroformation of 9 % water solution of polymer with technological additives and active substances.
It has been established that experimental models of nonwoven materials from
nanodimensional fibers on the basis of polyvinyl spirit with addition of tylosin tartratum with the crosslinking agent and without processing, with chlorhexidine bigluconate with the crosslinking agent and without processing possess the greatest antimicrobial activity with inhibition zones of museum test cultures of microorganisms E. coli ATCC 25922, S. aureus ATCC 25923, P. aeruginosa ATCC 27853, C. albicans АТСС 10231, B. subtilis, B. сereus АТСС 27853 from 1,66 mm to 9,66 mm.
The experimental models of nonwoven materials from nanodimensional fibers on the basis of polyvinyl spirit with chlorhexidine bigluconate, tylosin tartratum and soluble propolis became semitransparent and decreased in sizes on their dissolution in the suspension of microorganisms that testifies to their relative solubility.
The greatest zones of inhibition of museum test cultures of microorganisms E. coli ATCC 25922, S. aureus ATCC 25923, P. aeruginosa ATCC 27853, C. albicans АТСС 10231 from 7,6 to 10,6 mm were noted in samples of dressing materials with the nonwoven covering from polymeric nanofibers on the basis of polyvinyl spirit with tylosin tartratum and dycarboxilic acids. Other samples with chlorhexidine, propolis and tylosin tartratum also suppressed the growth of test cultures of microorganisms in the zones from 5,3 to 9,6 mm.
The results of the conducted research allow to conclude, that the wound electroformed nonwoven materials on the basis of polyvinyl spirit possess the antimicrobial activity and relative solubility and can be studied in the further tests for their application as dressing materials or «wound surfaces».
Key words: dressing material, nonwoven materials, nanodimensional fibers, electroformation, polyvinyl spirit, efficiency.

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Information about authors:
Miklis N.I. – Candidate of Medical Sciences, associate professor of the Chair of General Hygiene & Ecology, Vitebsk State Order of Peoples’ Friendship Medical University;
Alekseyev I.S. – Candidate of Technological Sciences, associate professor of the Chair of Technology & Equipment of Mechanical Engineering Production, Vitebsk State Technological University;
Doroshenko I.A. – laboratory assistant of the Chair of Technology & Equipment of Mechanical Engineering Production, Vitebsk State Technological University.

Correspondence address: Republic of Belarus, 210023, Vitebsk, 27 Frunze ave., Vitebsk State Order of Peoples’ Friendship Medical University, Chair of General Hygiene & Ecology. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.  – Natalya I. Miklis.

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