DOI: https://doi.org/10.22263/2312-4156.2018.3.89
Myadelets O.D.1, Lebedeva E.I.1, Myadelets N.Y.2
Teaching of stem cells theory at the chair of histology, cytology and embryology: tissue and organs regional stem cells. Part II
1Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
2Vitebsk State Medical College, Vitebsk, Republic of Belarus
Vestnik VGMU. 2018;17(3):89-102.
Abstract.
The article concludes a series of theoretical and educational materials on the functional cytology of the stem cells and their role in the regeneration of tissues and organs. This article considers regional stem cells of the vascular endothelium and blood vessels as a whole. Data on the stem cells of the pancreas and its regeneration at the tissue and organ levels are given. Regional stem cells of the air passages and the respiratory part of the lungs are considered. Different variants of posttraumatic lung regeneration at the organ level are discussed. In the section dedicated to the regional stem cells of the skin the description of various SC that restore the skin and its derivatives both under normal conditions and on its damage is provided. The possibilities of organotypical skin regeneration are discussed, including those based on the authors’ own scientific material. The techniques are proposed for using the material presented in the article in the educational process at the Chair of Histology, Cytology and Embryology.
Key words: regional stem cells, pancreas, lungs, skin.
References
1. Sarkisov DS. Pancreas. V: Aruin LI, Babaeva AG, Gel'fand VB; Sarkisov DS, red. Strukturnye osnovy adaptatsii i kompensatsii narushennykh funktsii: rukovodstvo. Moscow, RF: Meditsina; 1987. Р. 259-63. (In Russ.)
2. Timofeev AV. Cell-population organization of the pancreas and the use of cellular technologies in treatment of diabetes. V: Pal'tsev MA, red. Biologiia stvolovykh kletok i kletochnye tekhnologii. Moscow, RF: Meditsina; 2009. Т 2. Р. 253-310. (In Russ.)
3. Babaeva AG, Shubnikova EA. Structure, function and adaptive growth of salivary glands. Moscow, RF: MGU; 1979. 189 р. (In Russ.)
4. Vladimirskaya EB, Mayorova OA, Rumyantsev SA, Rumyantsev AG. Biological basis and prospects of stem cell therapy. Moscow, RF: MEDPRAKTIKA-M; 2005. 392 р. (In Russ.)
5. Artemova IA, Kozlova SN. Cell markers of endothelial damage associated with adverse prognosis in acute coronary events. Transliatsion Meditsina. 2017;4(1):41-8. (In Russ.)
6. Berezin UI, Kruzlyak P. Circulating endothelial apoptotic particles as a new marker of cardiovascular risk. Ukr Med Chasopis. 2014;9-10(5):83-7. (In Russ.)
7. Vorotelyak EA, Terskikh VV. Stem cells of epithelial tissues. V: Pal'tsev MA, red. Biologiia stvolovykh kletok i kletochnye tekhnologii. Moscow, RF: Meditsina; 2009. Т 2. Р. 53-74. (In Russ.)
8. Efimov EA. Post-traumatic regeneration of the skin. Moscow, RF: Meditsina; 1975. 168 р. (In Russ.)
9. Myadelets OD. Cellular mechanisms of barrier-protective functions of the skin and their disorders in skin diseases. Vitebsk, RB; 2000. 282 р. (In Russ.)
10. Myadelets OD, Adaskevich VP. Functional morphology and General pathology of the skin. Vitebsk, RB; 1997. 269 р. (In Russ.)
11. Myadelets OD, Adaskevich VP. Morphological dermatology. Moscow, RF: Med lit; 2006. 735 р. (In Russ.)
12. Myadelets OD, Sobolevskaya IS, Myadelets VO. Histophysiology fat-containing structures of the skin: ucheb posobie dlia studentov uchrezhdenii vyssh obrazovaniia po spetsial'nosti «Lechebnoe delo». Vitebsk, RB: VGMU; 2015. 290 р. (In Russ.)
13. Traktuev DO, Parfenova EV, Tkachuk VA, March KL. Stromal cells of adipose tissue-a plastic type of cells with a high therapeutic potential. Tsitologiia. 2006;48(2):83-94. (In Russ.)
14. Parfenova EV, Traktuev DO, Tkachuk VA. Adipose tissue stromal cells: molecular characteristics, antigenic properties and prospects for use in the treatment of cardiovascular diseases. V: Pal'tsev MA, red. Biologiia stvolovykh kletok i kletochnye tekhnologii. Moscow, RF: Meditsina; 2009. Т 2. Р. 4-35. (In Russ.)
15. Payushina OV, Starostin VI, Khrushchov NG. Multipotent mesenchymal stromal cells: characteristics, potencies to differentiation and prospects of clinical use. V: Pal'tsev MA, red. Biologiia stvolovykh kletok i kletochnye tekhnologii. Moscow, RF: Meditsina; 2009. Т 2. Р. 100-23. (In Russ.)
Information about authors:
Myadelets O.D. – Doctor of Medical Sciences, professor, head of the Chair of Histology, Cytology & Embryology, Vitebsk State Order of Peoples’ Friendship Medical University;
Lebedeva E.I. – Candidate of Biological Sciences, associate professor of the Chair of Histology, Cytology & Embryology, Vitebsk State Order of Peoples’ Friendship Medical University;
Myadelets N.Y. – lecturer of histology and genetics, Vitebsk State Medical College.
Correspondence address: Republic of Belarus, 210023, Vitebsk, 27 Frunze ave., Vitebsk State Order of Peoples’ Friendship Medical University, Chair of Histology, Cytology & Embryology. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Elena I. Lebedeva.
