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Karalkova N.K.1, Pristupa V.V.1, Katulskaya T.V.2
Tear replacement therapy in patients after phacoemulsification of cataracts
1Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Republic of Belarus
2Vitebsk Regional Clinical Hospital, Vitebsk, Republic of Belarus

Vestnik VGMU. 2019;18(1):52-58.

The research was performed at the department of eye microsurgery in the Vitebsk Regional Clinical Hospital. The article presents data of dynamic observation of changes in corneal thickness in 50 patients after performing cataract ultrasound phacoemulsification with the implantation of a soft intraocular lens during the first 5 days of the postoperative period with standard anti-inflammatory treatment and additional use of the drug based on cationic nanoemulsion as tear replacement therapy. Patients, with diabetes mellitus, diseases of the joints and connective tissue, glaucoma, inflammatory diseases of the choroid and refractive operations in their case history, were excluded from the research. Patients with corneal thickness less than 900 microns were included in it. It has been established that the use of cationic nanoemulsion containing glycerin in the early postoperative period accelerates the restoration of the normal thickness of the cornea, improves visual functions, reduces the rehabilitation term of patients after surgery. The drug possesses some properties of keratoprotector and osmocorrector, which enables recommendation of it for use beginning with the first days of the postoperative period after performing cataract phacoemulsification with the implantation of an intraocular lens in patients with corneal edema, that does not exceed 900 microns in thickness.
The article also lists the drugs of the “artificial tear” group, available for clinical use in the Republic of Belarus, with the indication of their active base, additional active ingredients, the presence or absence of a preservative, the possibility of applying directly to a contact lens.
Key words: tear replacement therapy, cationic nanoemulsion, cataract phacoemulsification, postoperative period.


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Information about authors:
Karalkova N.K. – Candidate of Medical Sciences, associate professor, acting head of the Chair of Ophthalmology, Vitebsk State Order of Peoples’ Friendship Medical University,
Pristupa V.V. – Candidate of Medical Sciences, associate professor of the Chair of Ophthalmology, Vitebsk State Order of Peoples’ Friendship Medical University;
Katulskaya T.V. – ophthalmologist, head of the department of eye microsurgery, Vitebsk Regional Clinical Hospital.

Correspondence address: Republic of Belarus, 210009, Vitebsk, 27 Frunze ave., Vitebsk State Order of Peoples’ Friendship Medical University, Chair of Ophthalmology. E-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра. – Natallia K. Karalkova.

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